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Neuroscience› Sensory Systems› Hearing, Cochlea, Tinnitus, Genetics

Tinnitus — Game-based frequency discrimination training

Submitted 2026-10-23

Field: Neuroscience › Sensory SystemsType: No effect foundArea: tinnitusTarget: Game-based frequency discrimination trainingStage: randomized trial

Hypothesis

Building auditory frequency training into a computer game would make people more motivated, so they would train more and their tinnitus would improve more than with standard task-based training.

What failed

In 60 participants over six weeks, the game versions felt more motivating, but compliance was about 70% in all three groups and tinnitus severity and attention did not change differently between groups.

Broken assumption

Making a therapy feel more enjoyable increases how much people do it and how much it helps.

Why

Higher reported motivation did not lead to more training or to more benefit.

From the published paper: Hoare et al. PLoS ONE, 2014. ↗CC BY

Research ideas from this failure

Unvetted lead — read the papers

New hypotheses this failure suggests, each with a crucial experiment, a rival explanation of the original result, and the papers it rests on. Written by AI from paper titles and abstracts found on OpenAlex (and Europe PMC, for life and health sciences).

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Links in published research

Where this experiment's genes are known to matter outside its own research area, and the papers behind those links. Sources: Open Targets Platform and Europe PMC.