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Environmental Science› Pollution› Microplastics and Plastic Pollution

Marine pollution — Polystyrene micro- and nanoplastics fed to Pacific oyster larvae

Submitted 2026-10-22

Field: Environmental Science › PollutionType: No effect foundArea: marine pollutionTarget: Polystyrene micro- and nanoplastics fed to Pacific oyster larvaeStage: full study

Hypothesis

Ingesting microplastics would impair the feeding and growth of Pacific oyster larvae.

What failed

Larvae readily ingested polystyrene particles from 70 nm to 20 μm, but exposure to 1 and 10 μm particles for up to 8 days had no significant effect on feeding or growth at under 100 microplastics per mL — concentrations above those observed in the sea.

Broken assumption

Ingesting microplastics at environmentally relevant or higher concentrations harms oyster larval feeding and growth in the short term.

Why

The paper reports no measurable effect on development or feeding over the study's duration; it does not propose a mechanism.

From the published paper: Cole et al. Environmental Science & Technology, 2015. ↗CC BY

Research ideas from this failure

Unvetted lead — read the papers

New hypotheses this failure suggests, each with a crucial experiment, a rival explanation of the original result, and the papers it rests on. Written by AI from paper titles and abstracts found on OpenAlex (and Europe PMC, for life and health sciences).

Related failures

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Links in published research

Where this experiment's genes are known to matter outside its own research area, and the papers behind those links. Sources: Open Targets Platform and Europe PMC.