failed_experiment.db
← Back to browse

Immunology and Microbiology› Parasitology› Vector-borne infectious diseases

Lyme disease prevention (health education) — Online educational video game on tick bites for schoolchildren

Submitted 2026-10-22

Field: Immunology and Microbiology › ParasitologyType: No effect foundArea: lyme disease prevention (health education)Target: Online educational video game on tick bites for schoolchildrenStage: randomized trial

Hypothesis

An online video game teaching Dutch schoolchildren about ticks and Lyme disease would improve knowledge, risk perception and tick-checking behaviour more than a leaflet or no intervention.

What failed

In a cluster-randomised study of 887 children aged 9-13 from 25 schools, knowledge rose in all three arms including the control, with no significant difference between interventions. Tick-checking rose in the game arm and beat the leaflet, but not by more than in the control group; overall the game did not outperform the leaflet or control on all outcomes.

Broken assumption

An interactive game teaches children health-protective knowledge better than passive materials, over and above the effect of being asked about the topic.

Why

The authors attribute the knowledge gain in the control group to a measurement effect from simply completing the questionnaire.

From the published paper: Beaujean et al. BMC Public Health, 2016. ↗CC BY

Research ideas from this failure

Unvetted lead — read the papers

New hypotheses this failure suggests, each with a crucial experiment, a rival explanation of the original result, and the papers it rests on. Written by AI from paper titles and abstracts found on OpenAlex (and Europe PMC, for life and health sciences).

Related failures

Nothing else logged looks close to this one yet.

Links in published research

Where this experiment's genes are known to matter outside its own research area, and the papers behind those links. Sources: Open Targets Platform and Europe PMC.